The Wyatt Lab
What We Do
Our overarching goal is to understand how human cells execute accurate DNA repair and maintain chromosome stability. The physiological significance of our research is underscored by the fact that defects in DNA repair and/or genome stability give rise to several deleterious diseases, including cancer. We use a powerful combination of in vitro and in vivo approaches and technologies to address our questions. Learn more about our research & experimental approaches below.
Research
Unlocking the Mysteries of DNA Nucleases in Genome Stability
We are interested in studying how the potentially damaging power of DNA nucleases is directed to safeguard genome integrity. Our long-term goal is to understand how human cells execute accurate DNA repair, a major barrier to the development of cancer.
You can find out more about our current research projects by clicking the link below.
Experimental Approaches
We use a powerful combination of complementary techniques in biochemistry and molecular biology to address our research questions.
Click on the images below to learn more.
Biochemistry
Molecular Biology
Contact Us
Thanks for your interest in our research. Get in touch with us for any questions or comments regarding our work. Individuals interested in joining the lab should check out the Available Positions page for more information.
University of Toronto, Department of Biochemistry
MaRS Center, West Tower, Room 1521A
661 University Avenue
Toronto, Ontario
M5G 1M1
1-416-978-4808 (office), 1-416-946-3440 (lab)